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Page 24

Arthroplasty 2019

June 24-25, 2019

Volume 14

Journal of Orthopaedics Trauma Surgery and Related Research


June 24-25, 2019 | Rome, Italy



International Conference on

Incidence and risk factors of acute kidney injury after total joint arthroplasty: A

retrospective cohort study

Izziddine Vial

University of Manchester, UK


Acute Kidney Injury (AKI) is a common complication post-arthroplasty, although it has not been extensively

studied. We carried out a retrospective study to determine the incidence and risk factors of AKI in patients undergoing

total joint arthroplasty (TJA).


Calculate the incidence of patients suffering from AKI after the changes made from the 2014 audit. Find out the

major pre- and perioperative risk factors of AKI in the cohort of patients.


We reviewed the medical records of all patients who underwent elective TJA from December 2014 to January

2017 at the Salford Royal Hospital, UK. AKI was defined using the AKIN, RIFLE and KDIGO criteria in patients with

worsened renal function post-arthroplasty. We analysed the association of the demographics, risk factors, medications

and use of peri-operative IV fluids with AKI. A logistic regression was performed to find any correlation between these

factors and incidence of AKI.


197 patients were included in our study, the mean age was 70.2 and male to female ratio was 6:5. Of these,

32(16.2%) developed an AKI. The multivariate logistic regression revealed 4 independent factors associated with the risk

of AKI; age (P =0.0011, OR 1.07, 95% CI 1.03-1.18), obesity (P =0.003, OR 6.4, 95% CI 2.34-17.5), smoking (P =0.0482,

OR 3.76, 95% CI 1.01-14.0) and COPD (P =0.0253, OR 3.85, 95% CI 1.18-12.5).


The incidence of AKI post-arthroplasty was found to be much higher than stated in other literatures. The

recognition of the high incidence and multiple independent risk factors will allow a better approach to peri-operative

management, limiting the risks of AKI. Our study also highlighted the importance of documenting urine output and the

need to repeat the renal function test 3 months after an AKI to assess recovery.


Izziddine Vial is an intercalating medical student at Hull York Medical School doing MSc in Clinical anatomy. He will continue his medical

studies at the University of Manchester as a 4th-year medical student. He has a special interest in trauma and orthopaedics.

Izziddine Vial, J.Orthop.Trauma Surg.Relat.Res. | Volume 14