Journal of Orthopaedics Trauma Surgery and Related Research

Journal of Orthopaedics Trauma Surgery and Related Research

An Official Journal of Polish Society of Orthopaedics and Traumatology

ISSN:1897-2276
e-ISSN: 2449-9145

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Efficacy of single dose versus multiple dose injectable antibiotics in hip joint surgery

Author(s): Nishit Bhatnagar*, Sumit Sural, Sumit Arora, Purushotham Lingaiah and Anil Dhal

Objective: To compare the efficacy of two prophylactic antibiotic regimens in preventing surgical site infection. Setting: Tertiary level hospital in India.

Methods: We enrolled 104 consecutive patients undergoing elective implant surgery around the hip and randomized them into two groups. Group A (53) received a single dose of injectable cefazolin prior to skin incision, while group B (51) received additional 5 doses of injection cefazolin 12 hourly after the procedure. They were followed up for a minimum duration of 12 months and observed for the evidence of surgical site infection.

Results: None of the patients from group A had surgical site infection, while 3 patients of group B (5.8%) developed infection. However, difference in infection rate was not significant statistically (p=0.114). Staphylococcus was isolated from 2 of the 3 infected surgical sites and Klebsiella from the third.

Conclusion: Additional postoperative doses of cefazolin offer no advantage over its single pre-operative dose.


Indexed in

Scopus Embase/EXPERTA MEDICA Road Directory of Open Access
Scholarly Resources
Publons MIAR GBL Ministry of Science and Higher
Education
Index Copernicus
SCImago Journal & Country Rank
Annals of Medical and Health Sciences Research Journal of Orthopaedics Trauma Surgery and Related Research a publication of Polish Society, is a peer-reviewed online journal with quaterly print on demand compilation of issues published.
Submit your Manuscript