High rate of postoperative complications and limited range of indications makes total ankle replacement (TAR) still a controversial procedure. Together with introduction of new biomaterials and improvement in the operative technique TAR becomes more attractive and interesting solution. As the implantation of the prosthesis in the joint without significant deformations is relatively easy, in cases with heavy posttraumatic changes may be very difficult. In such cases the choice of the appropriate implant is very important. This paper presents a case of the patient with secondary posttraumatic ostearthritis treated operatively with tatal ankle replacement using Mobility (DePuy) endoprosthesis. 1 year after the surgery the patient underwent clinical and radiographic evaluation including pedobarography and kinetic and kinematic gait analysis. Despite the disruption of the talofibular syndesmosis, total ankle replacement provided a good result of the treatment.