More than 200 million women are affected by osteoporosis globally, with postmenopausal women being more vulnerable to the disease’s severe side effects, such as osteoporotic fractures. Preventive methods have not yet received as much attention as symptomatic therapy has. In order to address this, we conducted a meta-analysis to determine possible predictors of osteoporotic fractures in postmenopausal women. The ultimate purpose of this was to identify high-risk individuals and investigate prospective therapy strategies. We may endeavor to lessen the burden of osteoporosis-related fractures in this vulnerable group by concentrating on preventative measures and identifying high-risk people.