Introduction. Total hip arthroplasty has become one of the most successful surgery procedure used in the treatment of osteoarthritis. More and more active, young patients undergo primary hip replacement. The aim of this study was to evaluate the influence of Mayo prosthesis and hip resurfacing on health-related quality of life. Materials and methods. The study was conducted at the Clinic of Orthopaedics and Traumatology, Jagiellonian University, Collegium Medicum. The study involved 38 patients: (X – age: 55±8,5), who underwent hip replacement surgery in 2005-2009. The modified SF-36 (Medical Outcomes Study 36-item Short Form), WOMAC (Western Ontario And McMaster Universities) and WHORQOL-100 questionnaire was used for research. The Quality of life was investigated before and after surgery. Results. After operation the improvement was observed in the following domains: physical, psychological, level of independence, social relations, ability to work, personal social relations, positive feelings and the global quality of life. Conclusions. Despite the short follow-up, Mayo prosthesis and hip resurfacing already represent valuable alternative for younger patients.