Introduction: Ochronosis is a rare inherited metabolic disorder caused by disturbance in tyrosine metabolism. It manifests as deposition of dark pigments in connective tissues and articular cartilage leading to arthropathy. Arthroplasty gives good functional outcome in severe ochronotic arthropathy. Case Report: A 56 years old female was admitted with advanced arthritis of left hip secondary to ochronosis. Total hip arthroplasty was performed. The results of the surgery in this patient was satisfactory. Conclusion: The functional result of total hip arthroplasty in ochronotic arthropathy is similar to primary osteoarthritis. Both cemented and uncemented hip arthroplasties have similar outcome in these hips.