An Official Journal of Polish Society of Orthopaedics and Traumatology
ISSN:1897-2276
e-ISSN: 2449-9145
Thomas Jefferson University, 4201 Henry Avenue, Philadelphia, United States
Opinion
Originating bone cancer: General health factors
Author(s):
KAYLEE JOHNSON*
Primary Bone Lymphoma (PBL) is a rare form of malignant lymphoma that primarily affects the skeletal system or various osseous sites. It differs from secondary lesions caused by disseminated lymphoma. PBL is defined as lymphoma localized to a single bone without distant spread for at least six months from initial diagnosis. It may involve regional lymph nodes and, rarely, manifests as multifocal lesions in more than one bone. PBL accounts for a small percentage of extra-nodal lymphomas and bone tumors, with a peak incidence in adults aged 40-60. It predominantly consists of diffuse large B cell lymphoma and can be categorized based on involvement and extent of disease. Diagnosis can be challenging due to factors like limited tissue samples and histological complexity. Common symptoms include localized bone pain, swelling, fractures, and neurological deficits. Laboratory tests may show.. Read More»
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