SUDHANSHU MISHRA

Department of Pharmaceutical Science, School of Pharmaceutical Science, Madhya Pradesh, India

Publications

• Original Article
  Arthritis-A leading cause of bone and joint disruption
  Author(s): SUDHANSHU MISHRA* and AISHWARYA SINGH RAJPUT
  
  Arthritis is typically joint inflammation that can generally affect one joint or several joints. There are over 100 different types of arthritis, with varying causes and methods of treatment. Osteoarthritis and rheumatoid arthritis are two of the most common types. Osteoarthritis can also cause inflammatory effects, but over time it often kills the joint cartilage. Rheumatoid arthritis is an autoimmune disorder that is causing symptoms of inflammatory joints throughout the body. Cytokines such as Interleukin 1 (IL-1) alpha, beta or Tumor Necrosis Factor (TNF)-alpha are powerful inductors of Metalloproteinases (MMPs) in synovial rheumatoid fibroblasts and are directly involved in joint destruction. To prevent these various conventional drugs are used like NSAIDs, corticosteroids, cytotoxic drugs etc., but the administration over a longer period may cause side effects. Herbal remedies a.. Read More»