Journal of Orthopaedics Trauma Surgery and Related Research

Journal of Orthopaedics Trauma Surgery and Related Research

An Official Journal of Polish Society of Orthopaedics and Traumatology

e-ISSN: 2449-9145

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Radial diffusivity role in classification of patients with antiphospholipid syndrome and “normal” radiological exams

Joint Event on 13th International Conference on ARTHRITIS AND RHEUMATOLOGY & 3rd International Conference on ANATOMY AND PHYSIOLOGY

December 9-10, 2019 | Barcelona, Spain

Shridevi Sandiramourty

Hospital of Nimes, France

Posters & Accepted Abstracts: J Orthop Trauma Surg Rel Res

Abstract :

Statement of the Problem: Antiphospholipid syndrome is defined as an autoimmune disease which is associated to thrombosis with common impact on MRI. However non-thrombolitic APS patients usually present “normal” routine MRI examinations. So, there is an interest to find a way to diagnostic them. Methodology & Theoretical Orientation: Diffusion-Tensor MRI (DT-MRI) was performed on 30 women with recurrent pregnancy loss (15 controls [C]; 15 antiphospholipid patients [APS] with high blood titre of Lupus Anticoagulant or Anti-b2- Glicoprotein-I antibodies). Assessed with Radial Diffusivity (RD), preceding study has demonstrated microstructural brain disruption in APS patients. Here, RD values were extracted within the significant clusters, in which voxels were considered attributes to perform Hoeffding tree classification. This is an incremental decision-tree learning model that assumes the distribution of data don’t change over time. Thus, small samples may be enough for optimal splitting threshold.

Findings: A total of 5225 attributes were found significant to produce 96.67% of accuracy (29 instances). Kappa statistics was 0.93, mean absolute error was 0.03 and the relative absolute error was 6.59%. All, but one control, subjects were correctly classified, resulting sensitivity of 1 and specificity of 0.93.

Conclusion & Significance: Radial Diffusivity index is an efficient attribute to classify patients with Antiphospholipid syndrome by means of Hoeffding tree algorithms. Moreover, RD values can be used as markers to follow the progression of the disease.

Biography :


Select your language of interest to view the total content in your interested language

20+ Million Readerbase
Indexed in

Embase/EXPERTA MEDICA Road Directory of Open Access
Scholarly Resources
Publons MIAR GBL Ministry of Science and Higher
Index Copernicus
Google Scholar citation report
Citations : 281

Journal of Orthopaedics Trauma Surgery and Related Research received 281 citations as per Google Scholar report

Journal of Orthopaedics Trauma Surgery and Related Research peer review process verified at publons
SCImago Journal & Country Rank
Annals of Medical and Health Sciences Research Journal of Orthopaedics Trauma Surgery and Related Research a publication of Polish Society, is a peer-reviewed online journal with quaterly print on demand compilation of issues published.
Submit your Manuscript