The spine is one of the essential structures in the human body, and it is the third most common site of abnormal cell proliferation, therefore, prompt evaluation and appropriate management of spinal pain and dysfunction is important. Spinal tumors may cause a variety of symptoms depending on their type, location, and rate of growth. Vertebroplasty is a minimally invasive, radiologically guided procedure that consist of percutaneous injection of a surgical cement into a vertebral body. In this study a total of 20 patients with 49 vertebral compression fractures underwent vertebroplasty at our institution. The aim of this study is to evaluate the role of vertebroplasty in management of o vertebral compression fractures in spine tumors, analysing the clinical and radiographic outcomes using the VAS and the DOI scores. The results were decreasing in VAS score from 8.65 to 1.8, and ODI score was 84.2, decreasing to 17.4 at the last follow-up visit.